Wired magazine has an excellent article that came out just today on the origins of the brain fog that seems to accompany long-haul covid. The author points out that the brain fog is quite similar to what happens when people who undergo chemotherapy get “chemo brain.”
In mice studies, according to researchers quoted in the article, certain microglia start over-reacting and begin eating away at needed neurons and other brain cells in the hippocampus. They also found that mice lost myelin (the protective coating around the axon of a nerve cell that is very much like the cord that surrounds wiring in electric cords on consumer goods such as lamps) in long-haul covid, and this loss of myelination causes memory issues.
These discoveries, they say, may lead to treatments.
I encourage you to read the Wired article, located here.